PT  - JOURNAL ARTICLE
AU  - Nicola Carlisle
AU  - Parameswaran Hari
AU  - Staley Brod
TI  - Plegia to walking: AHSCBMT in severe NMOSD relapse
AID  - 10.1136/bmjno-2020-000073
DP  - 2020 Oct 01
TA  - BMJ Neurology Open
PG  - e000073
VI  - 2
IP  - 2
4099  - http://neurologyopen.bmj.com/content/2/2/e000073.short
4100  - http://neurologyopen.bmj.com/content/2/2/e000073.full
SO  - BMJ Neurol Open2020 Oct 01; 2
AB  - Objectives Neuromyelitis optica is a devastating, relapsing, inflammatory, autoimmune disorder characterised in large part by attacks of optic neuritis and transverse myelitis causing blindness and plegia in many patients. Eighty-three per cent of patients with transverse myelitic attacks and 67% of patients with optic neuritis attacks have no or a partial recovery.Methods Results from The European Group for Blood and Marrow Transplantation Autoimmune Diseases Working Party imply failure of autologous haematopoietic stem cell bone marrow transplantation.Results and conclusion We present a case that despite eventual relapse, made a remarkable functional recovery after bone marrow transplantation which may justify bone marrow transplantation in severe cases.