PT - JOURNAL ARTICLE AU - Tan, Lynn AU - Lin, Zhiliang Caleb AU - Ray, Jason AU - Wesselingh, Robb AU - Oxley, Thomas J AU - McFadyen, James AU - Kapoor, Mahima AU - Hutton, Elspeth TI - Neurological implications of COVID-19: a review of the science and clinical guidance AID - 10.1136/bmjno-2020-000101 DP - 2020 Dec 01 TA - BMJ Neurology Open PG - e000101 VI - 2 IP - 2 4099 - http://neurologyopen.bmj.com/content/2/2/e000101.short 4100 - http://neurologyopen.bmj.com/content/2/2/e000101.full SO - BMJ Neurol Open2020 Dec 01; 2 AB - COVID-19 is a significant global health burden. The pulmonary morbidity and mortality of COVID-19 is well described, however, there is mounting evidence of neurological manifestations of SARS-CoV-2, which may be of prognostic significance. This paper summarises the available evidence in order to provide clinicians with a concise summary of the peripheral and central neurological manifestations of COVID-19, discusses specific issues regarding the management of chronic neurological disease in the context of the pandemic, and provides a summary of the thrombotic implications of the disease for the neurologist.