PT  - JOURNAL ARTICLE
AU  - Mariarosaria Valente
AU  - Ilaria Del Negro
AU  - Daniele Bagatto
AU  - Riccardo Garbo
AU  - Christian Lettieri
AU  - Andrea Bernardini
AU  - Annacarmen Nilo
AU  - Maria Rosaria Peri
AU  - Davide Pecori
AU  - Gian Luigi Gigli
TI  - Clinical and magnetic resonance study of a case of subacute sclerosing panencephalitis treated with ketogenic diet
AID  - 10.1136/bmjno-2021-000176
DP  - 2021 Jul 01
TA  - BMJ Neurology Open
PG  - e000176
VI  - 3
IP  - 2
4099  - http://neurologyopen.bmj.com/content/3/2/e000176.short
4100  - http://neurologyopen.bmj.com/content/3/2/e000176.full
SO  - BMJ Neurol Open2021 Jul 01; 3
AB  - Background Subacute sclerosing panencephalitis is a progressive neurodegenerative disorder caused by a latent and mutant measles virus which is extremely rare in developed countries. The lack of effective treatments leads to the research of other anti-inflammatory and neuroprotective treatments.Case Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet.Conclusions Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions.The data that support the findings of this short report are available on request from the corresponding author (IDN).