RT Journal Article
SR Electronic
T1 Clinical and magnetic resonance study of a case of subacute sclerosing panencephalitis treated with ketogenic diet
JF BMJ Neurology Open
JO BMJ Neurol Open
FD BMJ Publishing Group Ltd
SP e000176
DO 10.1136/bmjno-2021-000176
VO 3
IS 2
A1 Mariarosaria Valente
A1 Ilaria Del Negro
A1 Daniele Bagatto
A1 Riccardo Garbo
A1 Christian Lettieri
A1 Andrea Bernardini
A1 Annacarmen Nilo
A1 Maria Rosaria Peri
A1 Davide Pecori
A1 Gian Luigi Gigli
YR 2021
UL http://neurologyopen.bmj.com/content/3/2/e000176.abstract
AB Background Subacute sclerosing panencephalitis is a progressive neurodegenerative disorder caused by a latent and mutant measles virus which is extremely rare in developed countries. The lack of effective treatments leads to the research of other anti-inflammatory and neuroprotective treatments.Case Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet.Conclusions Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions.The data that support the findings of this short report are available on request from the corresponding author (IDN).