List | Enrolment/baseline | Day 0 | Day 1 | 1 month | 3 months | 6 months | 12 months |
Informed consent | ✓ | ||||||
Inclusion/exclusion criteria | ✓ | ||||||
Physical examination | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
Video assessment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
CT brain scan | ✓ | ||||||
Questionnaires (ADDS, MHOQ, TMDS/WCRS, SF-36, MMSE, BDI) | ✓ | ✓ | ✓ | ✓ | ✓ | ||
MRI | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Kinematic assessment | ✓ | ✓ | ✓ | ✓ | ✓ | ||
Neurophysiology | ✓ | ✓ | ✓ | ✓ | |||
Adverse event and serious adverse event assessment | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
ADDS, Arm Dystonia Disability Scale; BDI, Beck Depression Inventory; MHOQ, Michigan Hand Outcomes Questionnaire; MMSE, Mini-Mental State Examination; SF-36, Short Form-36; TMDS, Tubiana Musicians Dystonia Scale; WCRS, Writer’s Cramp Rating Scale.