Table 1

Baseline clinical characteristics

Placebo
(n=3)
Clozapine
(n=3)
Risperidone
(n=3)
% Female (n)67 (2)67 (2)100 (3)
Age (years)58 (12)57 (6)57 (9)
Bodyweight (kg)75.8 (21.6)89.4 (10.9)86.3 (26.6)
BMI (kg/m2)28.4 (3.7)30.8 (2.4)33.6 (7.9)
EDSS (±SD)6.3 (0.3)6.2 (0.6)6.2 (0.6)
FSS (±SD)6.4 (0.4)4.2 (1.5)6.3 (0.8)
MSFC (±SD)−1.41 (1.2)−0.91 (0.2)−0.76 (1.1)
hsCRP (±SD)3 (0)4 (1)5.7 (2.3)
TropT (±SD)11.3 (4.7)7.3 (4.0)5.3 (0.6)
Prolactin (±SD)194 (78)203 (87)200 (88)
  • BMI, body mass index; EDSS, Expanded Disability Status Scale; FSS, fatigue severity scale; hsCRP, high-sensitivity C reactive protein; MSFC, Multiple Sclerosis Functional Composite; TropT, troponin-T.