Changes to clinical parameters after risperidone treatment—3 months
| Parameter: mean (SD) | Time (months) | Placebo (n=3) | Risperidone (n=2) |
| Bodyweight (kg) | 0 | 75.9 (21) | 71.2 (6) |
| 3 | 75.8 (21) | 69.5 (3) | |
| BMI | 0 | 28.4 (4) | 29.3 (4) |
| 3 | 28.4 (4) | 28.6 (3) | |
| EDSS | 0 | 6.3 (0.3) | 6.0 (0.7) |
| 3 | 6.2 (0.3) | 6.3 (1.0) | |
| FSS | 0 | 6.4 (0.4) | 6.1 (1.0) |
| 3 | 6.1 (0.2) | 5.6 (1.0) | |
| MSFC | 0 | −1.4 (1.2) | −1.1 (1.2) |
| 3 | −1.1 (0.4) | −1.3 (1.1) | |
| WBC | 0 | 5.9 (1.1) | 7.5 (1.3) |
| 3 | 5.7 (0.9) | 6.9 (0.1) | |
| Neutrophils | 0 | 3.7 (0.3) | 4.7 (1.4) |
| 3 | 3.6 (0.2) | 4.5 (1.1) | |
| TropT | 0 | 11.3 (4.7) | 5.5 (0.7) |
| 3 | 13.0 (5.3) | 5.0 (0.0) | |
| CRP | 0 | 3.0 (0.1) | 5.0 (2.8) |
| 3 | 3.0 (0.1) | 4.5 (2.1) | |
| Prolactin (ng/mL) | 0 | 194 (78) | 216 (117) |
| 3 | 271 (154) | 4207 (1854) |
BMI, body mass index; CRP, C reactive protein; EDSS, Expanded Disability Status Scale; FSS, Functional System Score; MSFC, Multiple Sclerosis Functional Composite; TropT, troponin-T; WBC, white blood cell.