Pre- to post-treatment changes between the two groups at follow-up
| Topiramate | Lamotrigine | P value (<0.05) | |||
| Mdn | IQR | Mdn | IQR | ||
| Aura frequency per month | −2.4 | 3.4 | −4 | 3.9 | 0.28 |
| Duration of aura episodes (min) | −2.5 | 15 | −15 | 19 | 0.062 |
| Migraine attacks per month | −4.5 | 8 | −3.7 | 6.6 | 0.10 |
| Days of migraine per month | −6 | 3 | −4.7 | 5.3 | 0.37 |
| Rescue medication used per month | −5.5 | 5.5 | −5.5 | 6.6 | 0.44 |
IQR, interquartile range; Mdn, median.