Demographics and baseline clinical characteristics of study population
Topiramate | Lamotrigine | P value (<0.05) | |||
Sex (M/F) (%) | 3/22 | (12/88) | 3/25 | (11/89) | 0.60 |
Median age (years, range) | 46 | (23–66) | 37 | (18–84) | 0.021 |
Median age of migraine onset (years, range) | 18 | (6–48) | 15.5 | (6–38) | 0.058 |
Prior preventive treatment (%yes/%no) | 12/25 | (48/52) | 20/28 | (71/29) | 0.082 |
Median | Range | Median | Range | ||
Aura episodes per month | 4 | 1–15 | 4.5 | 1.5–15 | 0.18 |
Duration of aura episodes (min) | 28 | 5–90 | 30 | 5–90 | 0.44 |
Migraine attacks per month | 7 | 2.5–15 | 5 | 1.5–15 | 0.15 |
Days of migraine per month | 9 | 1.8–15 | 7.5 | 1.8–15 | 0.35 |
Rescue medication used per month | 10 | 2.5–15 | 9 | 1.5–15 | 0.51 |