Adults with moderate COVID-19 | Prophylactic anticoagulants, preferably low molecular weight heparins for example, enoxaparin 40 mg or dalteparin 5000 IU once daily If contraindicated, unfractionated heparin or renally adjusted doses of low-molecular-weight heparins may be used for example, enoxaparin 20 mg or dalteparin 2500 IU once daily
|
Severe or critical COVID-19, without contraindications | Consider increased prophylactic dosing, preferably low molecular weight heparins, for example, enoxaparin 40 mg or dalteparin 5000 IU two times per day In presence of acute kidney injury (creatinine clearance <30 mL/min), unfractionated heparin or renally adjusted doses of low-molecular-weight heparins may be used, for example, enoxaparin 40 mg or dalteparin 5000 IU once daily
|
All patients | Chemoprophylaxis should be combined with non-pharmacological measures such as rehydration Where VTE chemoprophylaxis is contraindicated, mechanical prophylaxis like intermittent pneumatic compression should be used
|