Correlation between topographic distribution of microbleeds and underlying medical history significant for either CABG, valve replacement or CAA
Amyloid (n=41) | CABG (n=21) | Valve (n=37) | P value* | CABG-Amyloid† | Valve-Amyloid† | Valve-CABG† | |
Total CMB | 18.0±25.9 | 3.5±2.3 | 4.1±4.1 | <0.01 | <0.01 | <0.01 | 0.99 |
Cortical | 15.5±20.4 | 2.0±1.0 | 2.7±2.7 | <0.01 | <0.01 | <0.01 | 0.98 |
SWM | 1.5±3.0 | 0.9±0.9 | 0.8±1.3 | 0.74 | 0.87 | 0.74 | 0.99 |
Ratio‡ | 0.05±0.08 | 0.26±0.28 | 0.18±0.17 | <0.01 | <0.01 | 0.01 | 0.25 |
*P value calculated using ANOVA.
†P value calculated using Tukey honest significant difference test.
‡Ratio=SWM/SWM+cortical microbleeds.
ANOVA, analysis of variance; CAA, cerebral amyloid angiopathy; CABG, coronary artery bypass grafting; CMB, cerebral microbleeds; SWM, subcortical white matter.