Outcome | Mean (SD) | Mean difference (95% CI) P value | ||
BL versus 6 weeks | BL versus 12 weeks | 6 weeks versus 12 weeks | ||
Speed | ||||
SRT speed | ||||
BL | 2.615 (0.107) | −0.036 | −0.030 | 0.007 |
6 weeks | 2.579 (0.085) | (−0.055 to –0.017) | (−0.049 to –0.010) | (−0.013 to 0.026) |
12 weeks | 2.586 (0.111) | <0.001 | 0.003 | 0.496 |
CRT speed | ||||
BL | 2.766 (0.080) | −0.019 | −0.019 | 0.000 |
6 weeks | 2.747 (0.074) | (−0.037 to –0.001) | (−0.037 to –0.001) | (−0.018 to 0.018) |
12 weeks | 2.746 (0.100) | 0.040 | 0.042 | 0.988 |
WM speed | ||||
BL | 2.970 (0.106) | −0.049 | −0.054 | −0.005 |
6 weeks | 2.921 (0.085) | (−0.070 to –0.028) | (−0.075 to –0.033) | (−0.026 to 0.016) |
12 weeks | 2.915 (0.093) | <0.001 | <0.001 | 0.623 |
CRT acc speed | ||||
BL | 1.450 (0.140) | 0.010 | −0.023 | −0.033 |
6 weeks | 1.460 (1.130) | (−0.050 to 0.029) | (−0.065 to 0.020) | (−0.077 to 0.011) |
12 weeks | 1.428 (0.153) | 0.599 | 0.293 | 0.141 |
WM acc speed | ||||
BL | 1.314 (0.184) | 0.110 | 0.034 | −0.076 |
6 weeks | 1.424 (0.155) | (0.063 to 0.157) | (−0.009 to 0.077) | (−0.115 to –0.037) |
12 weeks | 1.351 (0.162) | <0.001 | 0.125 | <0.001 |
Acc | ||||
SRT acc (%) | ||||
BL | 100.0 (97.0 to 100.0) | 0.0 | 0.0 | 0.0 |
6 weeks | 100.0 (97.0 to 100.0) | (0.0 to 0.0) | (0.0 to 0.0) | (0.0 to 0.0) |
12 weeks | 100.0 (97.0 to 100.0) | 0.358 | 0.709 | 0.917 |
CRT acc (%) | ||||
BL | 98.5 (97.0 to 100.0) | 0.0 | 0.0 | 0.0 |
6 weeks | 100.0 (97.0 to 100.0) | (0.0 to 0.0) | (0.0 to 0.0) | (−1.3 to 0.0) |
12 weeks | 97.0 (93.0 to 100.0) | 0.610 | 0.334 | 0.124 |
WM acc (%) | ||||
BL | 94.0 (87.0 to 97.0) | 3.0 | 0.0 | 0.0 |
6 weeks | 97.0 (94.0 to 100.0) | (0.0 to 6.0) | (0.0 to 3.0) | (−3.0 to 0.0) |
12 weeks | 94.0 (91.0 to 97.0) | <0.001 | 0.058 | 0.005 |
From BL to 6 weeks improved scores were demonstrated for all speed outcome variables, with reduction in time across all three outcomes (p<0.05).
From BL to 12 weeks all speed outcomes demonstrated improved score, with reduction in time across all three outcomes (p<0.05).
WM acc was the only accuracy score to show an improvement with a median increase of 3.0 from BL to 6 weeks (p<0.001).
acc, accuracy; BL, baseline; CRT, Choice Reaction Test; SRT, Simple Reaction Test; WM, working memory.