Discriminative features for each task by ET phenotype
Task | Feature | Control (median±SD) | ET-0 (median±SD) | ET+1 (median±SD) | ET+2 (median±SD) | P value | Spearman correlation coefficient |
Writing tasks | |||||||
1 | stdStrLen | 13.35±26.3 | 21.01±120 | 41.15±29.15 | 70.62±57.71 | 0.078* | 0.51 |
avgStrLenAir | 83.77±35.47 | 99.18±63.96 | 76.75±18.41 | 128.08±37.9 | 0.077* | 0.35 | |
2 | totalT | 6.2±0.42 | 6.33±0.24 | 6.14±0.19 | 6.58±0.21 | 0.01* | 0.39 |
ratioAxAy | 1±0.21 | 0.90±0.14 | 0.66±0.25 | 1.41±0.62 | 0.03* | 0.46 | |
3 | avgDiffP | 620.3±274.71 | 639.4±275.25 | 686±190.2 | 440±135.17 | 0.06* | −0.34 |
ratioAirSurT | 0.67±0.37 | 0.58±0.38 | 0.78±0.25 | 0.51±0.17 | 0.07* | −0.25 | |
4 | medAx | 1±0.62 | 0.5±0.18 | 0.5±0.22 | 1±0.92 | 0.03* | 0.59 |
avgAx | 2.5±4.3 | 1.39±0.6 | 1.23±3.7 | 2.87±7.44 | 0.053* | 0.55 | |
Drawing tasks | |||||||
5a | avgDiffP | 93.92±40.71 | 88.22±35.65 | 159.32±25.56 | 171.05±155.51 | 0.018* | 0.60 |
skewDiffP | 18.86±7.23 | 17.80±4.37 | 10.35±6.12 | 8.72±6.57 | 0.030* | −0.56 | |
5b | medAx | 0.25±0.07 | 0.25±0.20 | 0.50±0.11 | 0.875±1.92 | 0.042* | 0.58 |
Dxy | 33.5±16.49 | 39±104.11 | 120±55.41 | 176.50±206.5 | 0.068* | 0.54 | |
6 | medVx | 4.75±1.24 | 3.25±3.80 | 6±4.07 | 16.25±15.31 | 0.013* | 0.66 |
maxAngS | 21.17±28.0 | 21.15±9.44 | 22.01±8.73 | 16.76±59.76 | 0.016* | −0.54 | |
minStrLenAir | 82.50±41.65 | 103.50±54.12 | 9±48.59 | 7.50±30.45 | 0.017* | −0.65 | |
maxJx | 50.08±86.2 | 50.26±22.0 | 50.19±19.9 | 39.29±170.2 | 0.018* | −0.56 |
All features with p<0.05 are shown, otherwise the two features with lowest p values for each task. The p values and Spearman correlation coefficients were calculated for ET-0, ET+1 and ET+2.
*By Kruskal-Wallis.
ET, essential tremor.