Table 2

Cognitive measures at each visit

Baseline(n=28)Week 6 (n=28)Month 3 (n=27)Month 6 (n=23)Month 9 (n=18)Month 12 (n=16)Month 18 (n=10)
ADAS-Cog1121.7 (8–42.7)*NDND21.7 (5.33–43)†ND23.5 (8–51.7)‡26 (18.3–37.3)§
CFT9 (1–24)¶NDNDNDND7 (0–20)ND
COWAT24 (2–57)**NDNDNDND22 (3–38)††ND
DET2.64 (2.36–3.09)2.68 (2.38–3.17)2.70 (2.40–3.04)2.64 (2.39–2.98)2.67 (2.39–2.95)2.68 (2.39–2.99)2.79 (2.40–2.95
IDN2.81 (2.53–3.13)2.79 (2.69–3.08)*2.80 (2.63–3.09)2.81 (2.66–3.08)2.82 (2.66–2.98)2.85 (2.66–3.08)2.84 (2.73–3.08)
OCL0.766 (0.639–0.947)0.785 (0.563–0.935)*0.775 (0.358–0.924)0.805 (0.552–0.924)0.805 (0.515–0.947)0.78 (0.487–0.947)‡0.783 (0.717–0.9)

  • Data are presented as median (range).

  • *n=23.

  • †n=21.

  • ‡n=14.

  • §n=4.

  • ¶n=26.

  • **n=27.

  • ††n=15.

  • n=9.

  • ADAS-Cog11, Alzheimer’s Disease Assessment Scale—Cognitive Subscale; CFT, category fluency test; COWAT, controlled oral word association test; DET, detection reaction time task; IDN, identification reaction time task; OCL, one card learning memory task.