Table 2

Mean baseline and end of study PedsQL scale scores (full analysis set)

PedsQL scale score	Baseline		End of study
PedsQL scale score	Fingolimod N=107	IFN β-1a N=107	Fingolimod N=107	IFN β-1a N=107
Self-reported	(n=99)	(n=102)	(n=106)	(n=100)
Total Scale Score	78.06	80.13	82.59**	78.11
Physical Health Summary Score	80.62	82.51	84.84	79.79
Psychosocial Health Summary Score	76.70	78.92	81.40**	77.22
Emotional Functioning	71.11	75.69	77.22*	72.95
Social Functioning	90.66	90.15	91.98	88.85
School Functioning	68.33	70.84	74.91*	69.85
Parent-reported	(n=102)	(n=105)	(n=102)	(n=93)
Total Scale Score	75.42	78.45	78.98	76.80
Physical Health Summary Score	78.29	80.59	80.64	77.44
Psychosocial Health Summary Score	73.89	77.34	78.09	76.46
Emotional Functioning	68.58	73.10	74.02	72.10
Social Functioning	86.23	87.49	89.31	86.76
School Functioning	66.86	71.32	70.96	70.54

*p≤0.1, **p≤0.05 (both fingolimod vs IFN β-1a).
IFN, interferon; n, total number of patients with available results at baseline and included in the analysis; N, number of patients in the full analysis set; PedsQL, Pediatric Quality of Life.