Table 1

Baseline characteristics

CharacteristicsTotal
N=2890
Non-PAS
n=2210 (76.47%)
PAS
n=680 (23.53%)
P value
Age61.68±10.7960.90±10.8064.23±10.35<0.0001
BMI24.84±3.3024.85±3.2924.82±3.350.4375
Sex (female), n (%)874 (30.24)608 (27.51)266 (39.12)<0.0001
Medical history, n (%)
Ischaemic stroke544 (18.82)400 (18.10)144 (21.18)0.0727
 TIA42 (1.45)31 (1.40)11 (1.62)0.6821
 Myocardial infarction39 (1.35)26 (1.18)13 (1.91)0.1462
Atrial fibrillation71 (2.46)48 (2.17)23 (3.38)0.0746
 Hypertension1924 (66.57)1411 (63.85)513 (75.44)<0.0001
 Hyperlipidaemia210 (7.27)157 (7.10)53 (7.79)0.5444
 Diabetes mellitus693 (23.98)487 (22.04)206 (30.29)<0.0001
 Peripheral artery disease23 (0.80)17 (0.77)6 (0.88)0.7716
Smoking, n (%)955 (33.04)787 (35.61)168 (24.71)<0.0001
HbA1c (%)6.55±1.726.45±1.676.89±1.82<0.0001
 Missing1175896279
LDL (mmol/L)2.56±1.072.51±1.052.71±1.13<0.0001
 Missing1168234
Antiplatelet therapy, n (%)
 Single antiplatelet1196929 (42.04)267 (39.26)0.3449
 Dual antiplatelet16221229 (55.61)393 (57.79)
 None or missing7252 (2.35)20 (2.94)
Statin therapy, n (%)
 Statin standard treatment727 (25.16)551 (24.93)176 (25.88)0.6843
 Statin intensive treatment2163 (74.84)1659 (75.07)504 (74.12)0.6175
 Thrombolytic therapy, n (%)176 (6.09)139 (6.29)37 (5.44)0.4185
MRI features
 Diameter of infarction11.51±4.4111.47±4.3611.69±4.600.2017
Outcomes, n (%)
NIHSS score
 <41511 (52.28)1195 (54.07)316 (46.47)0.0005
 ≥41379 (47.72)1015 (45.93)364 (53.53)
3 months
 Ischaemic stroke152 (5.26)87 (3.94)65 (9.56)<0.0001
 Composite vascular event160 (5.54)91 (4.12)69 (10.15)<0.0001
 Haemorrhagic stroke4 (0.14)2 (0.09)2 (0.29)0.2117
mRS score
 0–22547 (89.34)1973 (90.50)574 (85.54)0.0003
 3–6304 (10.66)207 (9.50)97 (14.46)
 Missing39309
12 months
 Ischaemic stroke225 (7.79)137 (6.20)88 (12.94)<0.0001
 Composite vascular events254 (8.79)157 (7.10)97 (14.26)<0.0001
 Haemorrhagic stroke19 (0.66)14 (0.63)5 (0.74)0.7739
mRS score
 0–22561 (90.78)1986 (92.03)575 (86.73)<0.0001
 3–6260 (9.22)172 (7.97)88 (13.27)
 Missing695217
  • BMI, body mass index; HbA1c, haemoglobin A1c; LDL, low-density lipoprotein; mRS, modified Rankin Scale; NIHSS, National Institutes of Health Stroke Scale; PAS, parent artery stenosis; TIA, transient ischaemic attack.