Summary of previously published cases of Haycocknema perplexum myositis along with the two newly described cases in this report: clinical presentation, laboratory findings and overall patient outcomes
Year | Location | Age, sex | Exposures | Symptoms | Peak CK | Eosinophilia | Steroids | Outcome |
1994 | Tasmania | 33, F | Travel to Northern Territory Extensive animal exposure (botanist) Bush meat consumption | 5 years | 3294 | Yes (0.8) | Yes, deteriorated | Good recovery |
1996 | Tasmania | 48, M | Travel to North Queensland | 1.5 years | 1586 | Yes (2.0) | Ongoing weakness with improved CK (280) | |
2004 | Mackay, North Queensland | 61, M | Grew up in Tasmania | 3 years of dysphagia and dysarthria with 1 year of limb weakness | 1263 | Yes for 2 years | Yes - deteriorated | Deceased due to septic complications |
2005 | Innisfail, North Queensland | 23, F | Nil | 2 years of progressive weakness, weight loss and dysphagia | 1370 | Yes (1.1), elevated for prior 10 years | No | Ongoing weakness with improved CK (300) and resolved eosinophilia |
2006 | Mackay, North Queensland | 61, M | Nil | 2 years progressive weakness and dysphagia | 1230 | Yes (1.36), elevated for prior 2 years | No | Improved, ongoing mildly elevated CK (250) |
2011 | Tasmania | 50, M | Animal exposure (avid bush walker) Bush meat consumption | 2 years of progressive weakness, weight loss and dysphagia | 5700 | No | Yes - deteriorated | Improved weakness with persistent CK elevation (470) |
2012 | Cairns, North Queensland | 80, F | Extensive wildlife exposure (wildlife carer) Brief travel to Tasmania | 18 months of progressive weakness and weight loss | 270 | Yes (0.7) | No | Progressive weakness with normalisation of CK and eosinophillia |
2015 | Townsville, North Queensland | 30, M | Nil | 2 years of progressive proximal muscle weakness and weight loss | 3400 | Yes (1.24) | Yes, deteriorated | Good recovery |
2015 | Tasmania | 72, M | Animal exposure (hunter) Bush meat consumption | Years | 2082 | Yes (2.4) | Yes, deteriorated | Good recovery |
2021 | Townsville, North Queensland | 40s, M | Travel to Tasmania in youth Bush meat consumption | Subclinical | 2530 | Yes (2.1) | No | Asymptomatic |
2021 | Townsville, North Queensland | 20s, F | Nil | 3 years of progressive weakness and weight loss | 3162 | Yes (1.9) | No | Just commenced therapy |
CK, creatine kinase; F, female; M, male.