Baseline, admission and OTT variables | All | CVT | IVT only | MT only | IVT+MT |
Patient, N (%) | 63 964 (100.0) | 54 424 (85.1) | 8 405 (13.1) | 558 (0.9) | 577 (0.9) |
Age, mean years (SD) | 76.9 (11.7) | 77.5 (11.5) | 74.4 (12.0) | 71.7 (12.4) | 69.7 (12.8) |
Female, X (%) | 30 245 (47.3) | 25 943 (47.7) | 3 769 (44.8) | 268 (48.0) | 265 (45.9) |
NIHSS, median score (5th, IQR, 95th)* (N) | 4 (0, 1–8, 19) (37 039) | 3 (0, 1–6, 17) (28 313) | 7 (2, 4–12, 20) (7 660) | 14 (2, 10–18, 24) (516) | 15 (5, 11–19, 24) (550) |
Wake-up stroke, X (%) | 12 419 (23.0) | 11 566 (25.9) | 665 (8.0) | 147 (27.9) | 41 (7.2) |
Thrombolysis alert, X (%) | 23 058 (36.4) | 13 855 (25.8) | 8 162 (97.3) | 474 (86.3) | 567 (98.6) |
Recurrent stroke, X (%) | 9 964 (32.7) | 8 518 (35.0) | 1 313 (24.4) | 78 (24.5) | 55 (13.1) |
Interhospital transfer, X (%) | 1 307 (4.3) | 859 (3.5) | 281 (5.2) | 78 (24.5) | 89 (21.1) |
Modified RLS85 score††,(1–3) X (%) |
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Time in minutes from stroke onset to: | |||||
Hospital admission, median time (5th, IQR, 95th)* Mean time (SD) (N) | 156 (22, 100–310, 781) 246 (248) (31 343) | 199 (25, 107–400, 851) 288 (274) (22 562) | 112 (17, 85–184, 311) 136 (95) (7 832) | 115 (0, 83–302, 674) 211 (227) (392) | 100 (0, 70–136, 300) 117 (89) (557) |
Stroke unit admission, median time (5th, IQR, 95th)* Mean time (SD) (N) | 353 (105, 206–620, 1 126) 455 (331) (23 591) | 430 (127, 270–700, 1 210) 521 (340) (16 646) | 210 (86, 145–326, 811) 290 (236) (6 217) | 317 (0, 180–614, 1 214) 442 (368) (285) | 209 (70, 130–386, 881) 298 (254) (443) |
Intravenous thrombolysis, median time (5th, IQR, 95th)* Mean time (SD) (N) | 201 (99, 143–278, 404) 217 (98) (8 082) | N/A | 203 (100, 145–280, 405) 218 (98) (7 542) | N/A | 180 (91, 127–227, 376) 195 (97) (540) |
Mechanical thrombectomy, median time (5th, IQR, 95th)* Mean time (SD) (N) | 373 (175, 277–502, 770) 407 (199) (824) | N/A | N/A | 370 (170, 277–545, 942) 431 (239) (339) | 380 (190, 276–82, 714) 390 (164) (485) |
*(5th percentile, IQR, 95th percentile).
†Modified Reaction Level Scale: Assessment scale for patients’ consciousness level; 1=alert, 2=drowsy, 3=unconscious.
CVT, conservative therapy; IVT, intravenous thrombolysis; mRLS, modified Reaction Level Scale; MT, mechanical thrombectomy ; NIHSS, National Institutes of Health Stroke Scale; OTT, onset-to-treatment time .