Table 3

Therapies of LEMS patients with or without tumour

With tumour
(n=14)		Without tumour
(n=16)		P value
Therapies n (%)
 3,4-diaminopyridine (DAP)3 (21.4)9 (56.3)0.0717*
 AChEI8 (57.1)12 (75.0)0.4421*
 PSL2 (14.3)7 (43.8)0.1184*
 Maximum amount of PSL
 median (IQR)		40 (30–50))25 (20–30)0.2316†
 Immunosuppressant0 (0.0)4 (25.0)

  1. Azathioprine x2

  2. Tacrolimus x2

 Steroid pulse therapy3 (21.4)2 (12.5)0.6424*
 Plasmaphereesis14 (100)14 (87.5)0.4851*
 IVIg6 (42.9)5 (31.3)0.7065*

  • *Fisher’s exact test.

  • †Wilcoxon/Kruskal-Wallis test.

  • AChEI, acetylcholine esterase inhibitor; LEMS, Lambert-Eaton myasthenic syndrome; PSL, prednisolone.