Table 1

Summary of 1351 dementia trials completed between 2010 and 2021

CharacteristicN trials%
Results available on ClinicalTrials.gov (yes)38828.7
Type of dementia
 Alzheimer disease83261.6
 Delirium181.3
 Dementia32123.8
 Dementia with Lewy bodies282.1
 HIV dementia141.0
 Huntington disease785.8
 Mild cognitive impairment473.5
 Vascular dementia131.0
 Mild cognitive impairment (of any cause)20114.9
Type intervention
 Behavioural26619.7
 Biological382.8
 Device906.7
 Diagnostic test40.3
 Dietary supplement211.6
 Drug72253.4
 Genetic10.1
 Procedure201.5
 Radiation161.2
 Other17312.8
Trial phase
 Not applicable53439.5
 Phase 1/258243.1
 Phase 3/423517.4
Funding agency
 Industry48435.8
 Industry and NIH131.0
 Industry and other967.1
 NIH30.2
 NIH and other1118.2
 Other64447.7
 Randomisation (yes)91467.7
Location (continent)
 Africa50.4
 Americas72053.3
 Asia1339.8
 Europe30722.7
 Oceania110.8
 Worldwide17513.0
  • NIH, National Institutes of Health .