Characteristic | N trials | % |
Results available on ClinicalTrials.gov (yes) | 388 | 28.7 |
Type of dementia | ||
Alzheimer disease | 832 | 61.6 |
Delirium | 18 | 1.3 |
Dementia | 321 | 23.8 |
Dementia with Lewy bodies | 28 | 2.1 |
HIV dementia | 14 | 1.0 |
Huntington disease | 78 | 5.8 |
Mild cognitive impairment | 47 | 3.5 |
Vascular dementia | 13 | 1.0 |
Mild cognitive impairment (of any cause) | 201 | 14.9 |
Type intervention | ||
Behavioural | 266 | 19.7 |
Biological | 38 | 2.8 |
Device | 90 | 6.7 |
Diagnostic test | 4 | 0.3 |
Dietary supplement | 21 | 1.6 |
Drug | 722 | 53.4 |
Genetic | 1 | 0.1 |
Procedure | 20 | 1.5 |
Radiation | 16 | 1.2 |
Other | 173 | 12.8 |
Trial phase | ||
Not applicable | 534 | 39.5 |
Phase 1/2 | 582 | 43.1 |
Phase 3/4 | 235 | 17.4 |
Funding agency | ||
Industry | 484 | 35.8 |
Industry and NIH | 13 | 1.0 |
Industry and other | 96 | 7.1 |
NIH | 3 | 0.2 |
NIH and other | 111 | 8.2 |
Other | 644 | 47.7 |
Randomisation (yes) | 914 | 67.7 |
Location (continent) | ||
Africa | 5 | 0.4 |
Americas | 720 | 53.3 |
Asia | 133 | 9.8 |
Europe | 307 | 22.7 |
Oceania | 11 | 0.8 |
Worldwide | 175 | 13.0 |
NIH, National Institutes of Health .