Aβ42 | T-Tau | P-Tau | |||||||
b | 95% CI | P | b | 95% CI | p | b | 95% CI | p | |
All (n=135) | |||||||||
Awakening cortisol (t1) | 2.96 | −68.57 to 74.49 | 0.935 | 0.06 | −0.09 to 0.21 | 0.439 | 0.01 | −0.11 to 0.14 | 0.818 |
Bedtime cortisol (t6) | 21.67 | −17.67 to 61.01 | 0.278 | 0.05 | −0.04 to 0.13 | 0.272 | 0.02 | −0.05 to 0.08 | 0.620 |
Cortisol awakening response | −3.22 | −34.11 to 27.68 | 0.837 | 0.01 | −0.06 to 0.07 | 0.778 | 0.01 | −0.04 to 0.06 | 0.681 |
Daily cortisol output | 12.23 | −47.61 to 72.07 | 0.687 | 0.11 | −0.02 to 0.23 | 0.089 | 0.07 | −0.04 to 0.17 | 0.200 |
Cortisol AM/PM ratio (t1/t6) | −27.05 | −83.17 to 29.07 | 0.342 | –0.03 | −0.15 to 0.08 | 0.585 | −0.01 | −0.11 to 0.08 | 0.798 |
Results based on linear regressions. All analysis adjusted for age, sex and education.
*P<0.05, **p<0.01; ***p<0.001.
AD, Alzheimer’s disease ; Aβ, beta-amyloid; CSF, cerebrospinal fluid ; P-Tau, phosphorylated tau; T-TAU, total tau.