Table 1

Comparison of osmolarity change rates in each patient calculated by the changes in the serum ammonia concentration to a consensus on the safe range of the osmolarity change rates owing to serum Na+ concentration change

Our caseCardenas and Bodensteiner3Mattson et al2
Serum ammonia concentration (µmol/L)
before treatment
555253376
Serum ammonia concentration (µmol/L)
24 hours after treatment initiation
9633No data
Δ in serum ammonia concentration (µmol/L)
in 24 hours
–459–220(Not less than
–376)
Osmolarity change rate (mOsm/L/day)
due to Δ in serum ammonia concentration in 24 hours
–0.459–0.220(Not less than
–0.376)
Consensus on the safe range of
osmolarity change rates (mOsm/L/day)
due to Δ in serum Na+ concentration in 24 hours
±10
  • Δ, change.