Table 2

Incidence rates of outcome events

EventGroupNumberEventIncidence per 100 patient-years (95% CI)
Stroke/systemic embolic eventOverall2963951.73 (1.39 to 2.08)
Normal cognition2377741.65 (1.27 to 2.03)
Cognitive impairment586212.11 (1.21 to 3.01)
Major bleedingOverall2963470.85 (0.61 to 1.10)
Normal cognition2377340.75 (0.50 to 1.01)
Cognitive impairment586131.30 (0.59 to 2.01)
Intracranial haemorrhageOverall2963420.76 (0.53 to 0.99)
Normal cognition2377310.69 (0.44 to 0.93)
Cognitive impairment586111.10 (0.45 to 1.75)
Cardiovascular deathOverall2963581.05 (0.78 to 1.32)
Normal cognition2377350.77 (0.52 to 1.03)
Cognitive impairment586232.27 (1.35 to 3.20)
All-cause deathOverall29632043.68 (3.17 to 4.18)
Normal cognition23771082.38 (1.93 to 2.83)
Cognitive impairment586969.49 (7.60 to 11.39)
Net clinical outcomeOverall29632995.48 (4.86 to 6.10)
Normal cognition23771814.05 (3.46 to 4.64)
Cognitive impairment58611811.91 (9.76 to 14.06)