Baseline values for scores
| Baseline PP population (N=35) | Baseline MusiQoL index improved (n=21) | Baseline MusiQoL index worsened (n=14) | |
| Sex (n (%) | |||
| Male Female | 7 (33.3) 14 (66.7) | 7 (50.0) 7 (50.0) | |
| Education (n (%) | |||
| Primary education (basic) Secondary education (technical college) Tertiary education (university) | 7 (33.3) 9 (42.9) 5 (23.8) | 2 (14.3) 11 (28.6) 1 (7.1) | |
| MusiQoL index (N=35) | 66.7±13.8 | 66.2±13.3 | 67.4±15.1 |
| EDSS score (n=21) | 3.04±1.19 | 2.83±1.22 | 3.36±1.12 |
| ARR at baseline—all relapses (n=20) | 0.9±0.7 | 1.2±0.7 | 0.5±0.5 |
| ARR at baseline—relapses requiring steroid treatment (n=20) | 0.6±0.7 | 0.9±0.7 | 0.3±0.3 |
| FSMC total score (n=21) | 57.7±23.6 | 54.3±23.2 | 63.2±24.1 |
| BDI-FS (n=15) | 2.6±2.9 | 2.7±3.2 | 2.3±2.6 |
| SDMT (n=21) | 49.6±12.1 | 53.1±10.6 | 44.3±12.6 |
| MSISQ-19 total | 38.7±15.3 | 36.1±14.6 | 42.6±16.0 |
| MSISQ-19 primary causes of sexual dysfunction (n=21) | 10.8±5.7 | 9.7±5.3 | 12.6±6.0 |
| MSISQ-19 secondary causes of sexual dysfunction (n=21) | 18.3±6.6 | 17.5±6.7 | 19.6±6.4 |
| MSISQ-19 tertiary causes of sexual dysfunction (n=21) | 9.5±5.1 | 9.0±5.3 | 10.4±4.9 |
| EQ-5D index (n=21) | 0.838±0.151 | 0.853±0.126 | 0.814±0.184 |
| EQ-5D VAS (n=21) | 70.3±22.5 | 69.7±19.0 | 71.3±27.6 |
| WPAI presenteeism (n=12) | 30.0±30.1 | 35.0±32.1 | 15.0±19.1 |
| WPAI absenteeism (n=12) | 16.4±34.9 | 21.8±39.2 | 0 |
| WPAI productivity loss (n=12) | 38.7±35.6 | 46.6±36.9 | 15.0±19.1 |
| WPAI activity impairment (n=12) | 35.6±27.6 | 40.8±27.8 | 20.0±23.1 |
The results are shown as mean±SD. PROs were secondary outcomes; not all values were available for all 35 patients, particularly BDI-FS and WPAI.
ARR, annualised relapse rate; BDI, Beck Depression Inventory; EDSS, Expanded Disability Status Scale; EQ-5D, EuroQoL-5 Dimension; FSMC, Fatigue Scale of Motor and Cognitive Function; MSISQ, Multiple Sclerosis Intimacy and Sexuality Questionnaire-19; PRO, patient-reported outcome; SDMT, Symbol Digit Modalities Test; VAS, visual analogue scale; WPAI, Work Productivity and Activity Impairment in MS.