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Socioeconomic and occupational groups and Parkinson’s disease: a nationwide study based on hospitalizations in Sweden

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Abstract

Objectives

The aim of this study was to investigate whether there is an association between socioeconomic status, occupation and hospitalization for Parkinson’s disease (PD).

Methods

A nationwide database was constructed by linking the Swedish Census to the Hospital Discharge Register to obtain data on all first adult hospitalizations for PD diagnosed in Sweden during the study period from 1987 to 2004. Standardized incidence ratios (SIRs) with 95% confidence intervals (CIs) were calculated.

Results

A total of 8,870 males and 3,724 females first hospitalizations for PD were retrieved during the study period for adults aged 30 and older. Significantly increased SIRs for hospitalization for PD were found for men with high socioeconomic status. Among male occupations, increased SIRs were noted for several occupational groups such as teachers, administrators and managers, farmers, sales agents, wood workers, and painters and wall paperhangers. For female occupations, an increased risk was observed only among assistant nurses. The significant SIRs varied between 1.08 and 1.60.

Conclusions

The socioeconomic and occupational groups used in the present study have a relatively small effect on the population’s likelihood of hospitalization for PD but could give a notion of future research on specific occupational exposures.

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References

  • Andersson L, Eriksson R, Wärneryd B (1981) Att beskriva den sociala strukturen. Utvärdering av 1974 års förslag till socioekonomisk indelning. (Describing the social structure. Evaluation of the proposal for socioeconomic classification). Swedish Statistisk Tidskrift 2:113–136

    Google Scholar 

  • Borm PJ, Jetten M, Hidayat S, van de Burgh N, Leunissen P, Kant I, Houba R, Soeprapto H (2002) Respiratory symptoms, lung function, and nasal cellularity in Indonesian wood workers: a dose–response analysis. Occup Environ Med 59:338–344

    Article  PubMed  CAS  Google Scholar 

  • Demers PA, Boffetta P (1998) Cancer risk from occupational exposure to wood dust: a pooled analysis of epidemiological studies. IARC, Lyon

    Google Scholar 

  • Frigerio R, Elbaz A, Sanft KR, Peterson BJ, Bower JH, Ahlskog JE, Grossardt BR, de Andrade M, Maraganore DM, Rocca WA (2005) Education and occupations preceding Parkinson disease: a population-based case–control study. Neurology 65:1575–1583

    Article  PubMed  CAS  Google Scholar 

  • Gorell JM, Johnson CC, Rybicki BA, Peterson EL, Richardson RJ (1998) The risk of Parkinson’s disease with exposure to pesticides, farming, well water, and rural living. Neurology 50:1346–1350

    PubMed  CAS  Google Scholar 

  • Hemminki K, Li X (2002a) Cancer risks in Nordic immigrants and their offspring in Sweden. Eur J Cancer 38:2428–2434

    Article  PubMed  CAS  Google Scholar 

  • Hemminki K, Li X (2002b) Cancer risks in second-generation immigrants to Sweden. Int J Cancer 99:229–237

    Article  PubMed  CAS  Google Scholar 

  • Hemminki K, Li X, Czene K (2002) Cancer risks in first-generation immigrants to Sweden. Int J Cancer 99:218–228

    Article  PubMed  CAS  Google Scholar 

  • Kirkey KL, Johnson CC, Rybicki BA, Peterson EL, Kortsha GX, Gorell JM (2001) Occupational categories at risk for Parkinson’s disease. Am J Ind Med 39:564–571

    Article  PubMed  CAS  Google Scholar 

  • Kuopio AM, Marttila RJ, Helenius H, Rinne UK (1999) Environmental risk factors in Parkinson’s disease. Mov Disord 14:928–939

    Article  PubMed  CAS  Google Scholar 

  • Lai BC, Marion SA, Teschke K, Tsui JK (2002) Occupational and environmental risk factors for Parkinson’s disease. Parkinsonism Relat Disord 8:297–309

    Article  PubMed  CAS  Google Scholar 

  • Landtblom AM, Tondel M, Hjalmarsson P, Flodin U, Axelson O (2006) The risk for multiple sclerosis in female nurse anaesthetists: a register based study. Occup Environ Med 63:387–389

    Article  PubMed  Google Scholar 

  • McDonnell L, Maginnis C, Lewis S, Pickering N, Antoniak M, Hubbard R, Lawson I, Britton J (2003) Occupational exposure to solvents and metals and Parkinson’s disease. Neurology 61:716–717

    PubMed  CAS  Google Scholar 

  • Pezzoli G, Canesi M, Antonini A, Righini A, Perbellini L, Barichella M, Mariani CB, Tenconi F, Tesei S, Zecchinelli A et al (2000) Hydrocarbon exposure and Parkinson’s disease. Neurology 55:667–673

    PubMed  CAS  Google Scholar 

  • Priyadarshi A, Khuder SA, Schaub EA, Priyadarshi SS (2001) Environmental risk factors and Parkinson’s disease: a metaanalysis. Environ Res 86:122–127

    Article  PubMed  CAS  Google Scholar 

  • Rocca WA, Anderson DW, Meneghini F, Grigoletto F, Morgante L, Reggio A, Savettieri G, Di Perri R (1996) Occupation, education, and Parkinson’s disease: a case–control study in an Italian population. Mov Disord 11:201–206

    Article  PubMed  CAS  Google Scholar 

  • Rosén M, Hakulinen T (2005) Use of disease registers. In: Ahrens W, Pigeot I (eds) Handbook of epidemiology. Springer, Berlin

    Google Scholar 

  • Rothman KJ, Greenland S (1998) Modern epidemiology, 2nd edn edn. Lippincott-Raven, Philadelphia

    Google Scholar 

  • Statistics Sweden (2005) The Swedish Multi Generation Register (1960–1990): http://www.scb.se/templates/Standard_22842.asp (in Swedish: Registret över totalbefolkningen/RTB)

  • Sundquist K, Li X, Hemminki K (2006) Familial risks of hospitalization for Parkinson’s disease in first-degree relatives: a nationwide follow-up study from Sweden. Neurogenetics 7:231–237

    Article  PubMed  Google Scholar 

  • Tanner CM, Ottman R, Goldman SM, Ellenberg J, Chan P, Mayeux R, Langston JW (1999) Parkinson disease in twins: an etiologic study. JAMA 281:341–346

    Article  PubMed  CAS  Google Scholar 

  • The National Board of Health and Welfare (2004) The Swedish Hospital Discharge Register and the Cause of Death Register (1961–2001). http://www.sos.se/epc/english/ParEng.htm

  • Tsui JK, Calne DB, Wang Y, Schulzer M, Marion SA (1999) Occupational risk factors in Parkinson’s disease. Can J Public Health 90:334–337

    PubMed  CAS  Google Scholar 

  • Vieregge P, Schiffke KA, Friedrich HJ, Muller B, Ludin HP (1992) Parkinson’s disease in twins. Neurology 42:1453–1461

    PubMed  CAS  Google Scholar 

  • Warneryd B, Ostlin P, Thorslund M (1989) Living conditions. Appendix 11. Quality in retrospective questions on previous occupational exposures: an evaluation of occupational histories in the investigation on living conditions. Statistics Sweden, Stockholm

    Google Scholar 

  • Wirdefeldt K, Gatz M, Schalling M, Pedersen NL (2004) No evidence for heritability of Parkinson disease in Swedish twins. Neurology 63:305–11

    PubMed  Google Scholar 

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Acknowledgments

This work was supported by grants from the National Heart, Lung, and Blood Institute (R01-H271084-1) and The National Institute of Child Health and Human Development (1R01HD052848-01), the Swedish Research Council (K2005-27X-15428-01A), the Swedish Council for Working Life and Social Research (2006-0386 and 2007-1754), and The Swedish Research Council Formas (2006-4255-6596-99 and 2007-1352).

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Li, X., Sundquist, J. & Sundquist, K. Socioeconomic and occupational groups and Parkinson’s disease: a nationwide study based on hospitalizations in Sweden. Int Arch Occup Environ Health 82, 235–241 (2009). https://doi.org/10.1007/s00420-008-0327-z

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  • DOI: https://doi.org/10.1007/s00420-008-0327-z

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