User profiles for "author:Andreas Lutterotti"
Andreas LutterottiUniversity of Zürich Verified email at usz.ch Cited by 2997 |
Pathophysiological and cognitive mechanisms of fatigue in multiple sclerosis
ZM Manjaly, NA Harrison, HD Critchley… - Journal of Neurology …, 2019 - jnnp.bmj.com
Fatigue is one of the most common symptoms in multiple sclerosis (MS), with a major impact
on patients' quality of life. Currently, treatment proceeds by trial and error with limited …
on patients' quality of life. Currently, treatment proceeds by trial and error with limited …
Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper)
Multiple sclerosis is a complex, autoimmune-mediated disease of the central nervous
system characterized by inflammatory demyelination and axonal/neuronal damage. The …
system characterized by inflammatory demyelination and axonal/neuronal damage. The …
[HTML][HTML] Complement activating antibodies to myelin oligodendrocyte glycoprotein in neuromyelitis optica and related disorders
S Mader, V Gredler, K Schanda, K Rostasy… - Journal of …, 2011 - Springer
Background Serum autoantibodies against the water channel aquaporin-4 (AQP4) are
important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO) …
important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO) …
Antigen-specific tolerance by autologous myelin peptide–coupled cells: a phase 1 trial in multiple sclerosis
Multiple sclerosis (MS) is a devastating inflammatory disease of the brain and spinal cord
that is thought to result from an autoimmune attack directed against antigens in the central …
that is thought to result from an autoimmune attack directed against antigens in the central …
[PDF][PDF] Memory B cells activate brain-homing, autoreactive CD4+ T cells in multiple sclerosis
Multiple sclerosis is an autoimmune disease that is caused by the interplay of genetic,
particularly the HLA-DR15 haplotype, and environmental risk factors. How these etiologic …
particularly the HLA-DR15 haplotype, and environmental risk factors. How these etiologic …
Getting specific: monoclonal antibodies in multiple sclerosis
A Lutterotti, R Martin - The Lancet Neurology, 2008 - thelancet.com
For more than a decade the only therapies that were available for multiple sclerosis (MS)
were two immunomodulatory drugs—interferon beta and glatiramer acetate—and the …
were two immunomodulatory drugs—interferon beta and glatiramer acetate—and the …
EBNA1-specific T cells from patients with multiple sclerosis cross react with myelin antigens and co-produce IFN-γ and IL-2
Symptomatic primary Epstein-Barr virus (EBV) infection and elevated humoral immune
responses to EBV are associated with an increased risk of developing multiple sclerosis …
responses to EBV are associated with an increased risk of developing multiple sclerosis …
Treatment of MOG-IgG-associated disorder with rituximab: an international study of 121 patients
DH Whittam, A Cobo-Calvo… - Multiple sclerosis and …, 2020 - Elsevier
Objective To assess the effect of anti-CD20 B-cell depletion with rituximab (RTX) on relapse
rates in myelin oligodendrocyte glycoprotein antibody-associated disorder (MOGAD) …
rates in myelin oligodendrocyte glycoprotein antibody-associated disorder (MOGAD) …
[HTML][HTML] Patterns of antibody binding to aquaporin-4 isoforms in neuromyelitis optica
S Mader, A Lutterotti, F Di Pauli, B Kuenz, K Schanda… - PloS one, 2010 - journals.plos.org
Background Neuromyelitis optica (NMO), a severe demyelinating disease, represents itself
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …
with optic neuritis and longitudinally extensive transverse myelitis. Serum NMO-IgG …
[PDF][PDF] HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis
The HLA-DR15 haplotype is the strongest genetic risk factor for multiple sclerosis (MS), but
our understanding of how it contributes to MS is limited. Because autoreactive CD4+ T cells …
our understanding of how it contributes to MS is limited. Because autoreactive CD4+ T cells …