User profiles for "author:Henrik Zetterberg"

Henrik Zetterberg

Sahlgrenska
Verified email at clinchem.gu.se
Cited by 144301

Alzheimer's disease

K Blennow, MJ de Leon, H Zetterberg - The Lancet, 2006 - thelancet.com
Alzheimer's disease is the most common cause of dementia. Research advances have
enabled detailed understanding of the molecular pathogenesis of the hallmarks of the …

Cerebrospinal fluid and plasma biomarkers in Alzheimer disease

K Blennow, H Hampel, M Weiner… - Nature Reviews …, 2010 - nature.com
Intense multidisciplinary research has provided detailed knowledge of the molecular
pathogenesis of Alzheimer disease (AD). This knowledge has been translated into new …

CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis

B Olsson, R Lautner, U Andreasson, A Öhrfelt… - The Lancet …, 2016 - thelancet.com
Background Alzheimer's disease biomarkers are important for early diagnosis in routine
clinical practice and research. Three core CSF biomarkers for the diagnosis of Alzheimer's …

Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study

O Hansson, H Zetterberg, P Buchhave… - The Lancet …, 2006 - thelancet.com
Background Disease-modifying treatment strategies for Alzheimer's disease have led to an
urgent need for biomarkers to identify the disease at a very early stage. Here, we assess the …

Defeating Alzheimer's disease and other dementias: a priority for European science and society

B Winblad, P Amouyel, S Andrieu, C Ballard… - The Lancet …, 2016 - thelancet.com
Executive summary Alzheimer's disease (AD) is the leading cause of dementia, and
because the primary risk factor for AD is old age, the prevalence of the disease is increasing …

A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease

DP Wightman, IE Jansen, JE Savage, AA Shadrin… - Nature …, 2021 - nature.com
Late-onset Alzheimer's disease is a prevalent age-related polygenic disease that accounts
for 50–70% of dementia cases. Currently, only a fraction of the genetic variants underlying …

Blood-based biomarkers for Alzheimer's disease: towards clinical implementation

CE Teunissen, IMW Verberk, EH Thijssen… - The Lancet …, 2022 - thelancet.com
For many years, blood-based biomarkers for Alzheimer's disease seemed unattainable, but
recent results have shown that they could become a reality. Convincing data generated with …

[PDF][PDF] Hallmarks of neurodegenerative diseases

DM Wilson, MR Cookson, L Van Den Bosch… - Cell, 2023 - cell.com
Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …

[HTML][HTML] Gut microbiome alterations in Alzheimer's disease

NM Vogt, RL Kerby, KA Dill-McFarland, SJ Harding… - Scientific reports, 2017 - nature.com
Alzheimer's disease (AD) is the most common form of dementia. However, the
etiopathogenesis of this devastating disease is not fully understood. Recent studies in …

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis

WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms… - Jama, 2015 - jamanetwork.com
Importance Cerebral amyloid-β aggregation is an early pathological event in Alzheimer
disease (AD), starting decades before dementia onset. Estimates of the prevalence of …