User profiles for "author:James J M Loan"

James JM Loan

ECAT Clinical Lecturer, University of Edinburgh
Verified email at nhs.net
Cited by 607

The relationship of the FOUR score to patient outcome: a systematic review

CC Foo, JJM Loan, PM Brennan - Journal of Neurotrauma, 2019 - liebertpub.com
Abstract The Full Outline of UnResponsiveness (FOUR) score assessment of consciousness
replaces the Glasgow Coma Scale (GCS) verbal component with assessment of brainstem …

[HTML][HTML] Activation of Nrf2 to optimise immune responses to intracerebral haemorrhage

JJM Loan, R Al-Shahi Salman, BW McColl… - Biomolecules, 2022 - mdpi.com
Haemorrhage into the brain parenchyma can be devastating. This manifests as
spontaneous intracerebral haemorrhage (ICH) after head trauma, and in the context of …

[HTML][HTML] Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies

L Li, MTC Poon, NE Samarasekera, LA Perry… - The Lancet …, 2021 - thelancet.com
Background Patients with stroke due to spontaneous (non-traumatic) intracerebral
haemorrhage (ICH) are at risk of recurrent ICH, ischaemic stroke, and other serious vascular …

Medically induced hypertension, hypervolaemia and haemodilution for the treatment and prophylaxis of vasospasm following aneurysmal subarachnoid haemorrhage …

JJM Loan, AN Wiggins, PM Brennan - British Journal of …, 2018 - Taylor & Francis
Purpose: Arterial vasospasm is a major cause of death and long-term disability following
subarachnoid haemorrhage (SAH). The use of medically induced hypertension …

Association between computed tomographic biomarkers of cerebral small vessel diseases and long‐term outcome after spontaneous intracerebral hemorrhage

MA Rodrigues, NE Samarasekera… - Annals of …, 2021 - Wiley Online Library
Objective A study was undertaken to assess whether cerebral small vessel disease (SVD)
computed tomographic (CT) biomarkers are associated with long‐term outcome after …

Pre-operative obesity does not predict poorer symptom control and quality of life after lumbar disc surgery

PM Brennan, JJM Loan, N Watson… - British Journal of …, 2017 - Taylor & Francis
Purpose: We aimed to determine whether there was a difference in post-operative
symptomatic control and quality of life (QoL) between patients who were obese (BMI> 30) …

Feasibility of comparing medical management and surgery (with neurosurgery or stereotactic radiosurgery) with medical management alone in people with …

JJM Loan, A Bacon, J van Beijnum, P Bhatt… - BMJ open, 2023 - bmjopen.bmj.com
Introduction The top research priority for cavernoma, identified by a James Lind Alliance
Priority setting partnership was 'Does treatment (with neurosurgery or stereotactic …

Secondary injury and inflammation after intracerebral haemorrhage: a systematic review and meta-analysis of molecular markers in patient brain tissue

JJM Loan, C Kirby, K Emelianova… - Journal of Neurology …, 2022 - jnnp.bmj.com
Background Inflammatory responses to intracerebral haemorrhage (ICH) are potential
therapeutic targets. We aimed to quantify molecular markers of inflammation in human brain …

[HTML][HTML] Nrf2 activation in the human brain after stroke due to supratentorial intracerebral haemorrhage: a case–control study

E Christopher, JJM Loan, N Samarasekera… - BMJ Neurology …, 2022 - ncbi.nlm.nih.gov
Aims Pharmacological activation of the antioxidative transcription factor nuclear factor
erythroid 2-related factor 2 (Nrf2) improves outcomes in experimental models of …

Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: a community …

JJM Loan, AB Gane, L Middleton… - … journal of stroke, 2021 - journals.sagepub.com
Background Hospital-based studies have reported variable associations between outcome
after spontaneous intracerebral hemorrhage and peri-hematomal edema volume. Aims In a …