The controversy as to whether Doppler ultrasonic methods should play a role in clinical
decision-making in the prevention of stroke is attributable to reported disagreement between …

Wider use of oral anticoagulants has led to an increasing frequency of warfarin-related
intracerebral hemorrhage (ICH). The high early mortality of approximately 50% has …

In Japan, intravenous alteplase, a recombinant tissue-type plasminogen activator (rt-PA),
was approved for an indication of ischemic stroke in 2005 on the basis of the results of a …

Background and Purpose—We sought to determine the incidence and severity of bleeding
events in patients with stroke and cardiovascular diseases who were taking oral …

Objective To determine optimal intensity of international normalized ratio (INR) of warfarin
therapy for the prevention of ischemic events in patients with non-valvular atrial fibrillation …

We investigated the effect of prothrombin complex concentrate (PCC, median 500 IU) and
vitamin K (10–20 mg) or either on blood coagulation and clinical findings in 17 patients with …

Background and Purpose—Several risk scores have been developed to predict the stroke
risk after transient ischemic attack (TIA). However, the validation of these scores in different …

The Japanese Circulation Society (JCS) published the “Guidelines for Pharmacological
Treatment of Arrhythmia” in 2004, and a revised edition was published in 2009. 1 Both …

Background Vascular endothelial growth factor (VEGF) is a well-known molecule mediating
neuronal survival and angiogenesis. However, its clinical significance in ischemic stroke is …

We studied the frequency and grade of atherosclerotic changes in the thoracic aorta and
their significance as embologenic lesions in patients with stroke. Using transesophageal …