User profiles for "author:Neshika Samarasekera"

Neshika Samarasekera

Consultant neurologist
Verified email at ed.ac.uk
Cited by 3906

Brain hemorrhage recurrence, small vessel disease type, and cerebral microbleeds: a meta-analysis

A Charidimou, T Imaizumi, S Moulin, A Biffi… - Neurology, 2017 - AAN Enterprises
Objective: We evaluated recurrent intracerebral hemorrhage (ICH) risk in ICH survivors,
stratified by the presence, distribution, and number of cerebral microbleeds (CMBs) on MRI …

Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study

A Varatharaj, N Thomas, MA Ellul, NWS Davies… - The Lancet …, 2020 - thelancet.com
Background Concerns regarding potential neurological complications of COVID-19 are
being increasingly reported, primarily in small series. Larger studies have been limited by …

The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis

N Samarasekera, C Smith, RAS Salman - Journal of Neurology …, 2012 - jnnp.bmj.com
Background The aim of this study was to determine the strength of the association between
intracerebral haemorrhage (ICH) and cerebral amyloid angiopathy (CAA) in a systematic …

APOE associations with severe CAA-associated vasculopathic changes: collaborative meta-analysis

K Rannikmäe, RN Kalaria, SM Greenberg… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objectives Cerebral amyloid angiopathy (CAA) is associated with lobar intracerebral
haemorrhage (ICH). While only the ε4 allele of the apolipoprotein E (APOE) gene is …

The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study

A Charidimou, G Boulouis, MP Frosch… - The Lancet …, 2022 - thelancet.com
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …

[HTML][HTML] The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and …

MA Rodrigues, N Samarasekera, C Lerpiniere… - The Lancet …, 2018 - thelancet.com
Background Identification of lobar spontaneous intracerebral haemorrhage associated with
cerebral amyloid angiopathy (CAA) is important because it is associated with a higher risk of …

[HTML][HTML] Deposition of amyloid β in the walls of human leptomeningeal arteries in relation to perivascular drainage pathways in cerebral amyloid angiopathy

A Keable, K Fenna, HM Yuen, DA Johnston… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Deposition of amyloid β (Aβ) in the walls of cerebral arteries as cerebral amyloid angiopathy
(CAA) suggests an age-related failure of perivascular drainage of soluble Aβ from the brain …

Influence of intracerebral hemorrhage location on incidence, characteristics, and outcome: population-based study

N Samarasekera, A Fonville, C Lerpiniere, AJ Farrall… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The characteristics of intracerebral hemorrhage (ICH) may vary
by ICH location because of differences in the distribution of underlying cerebral small vessel …

[HTML][HTML] Risks of recurrent stroke and all serious vascular events after spontaneous intracerebral haemorrhage: pooled analyses of two population-based studies

L Li, MTC Poon, NE Samarasekera, LA Perry… - The Lancet …, 2021 - thelancet.com
Background Patients with stroke due to spontaneous (non-traumatic) intracerebral
haemorrhage (ICH) are at risk of recurrent ICH, ischaemic stroke, and other serious vascular …

Effects of oral anticoagulation for atrial fibrillation after spontaneous intracranial haemorrhage in the UK: a randomised, open-label, assessor-masked, pilot-phase, non …

RAS Salman, C Keerie, J Stephen, S Lewis… - The Lancet …, 2021 - thelancet.com
Background Oral anticoagulation reduces the rate of systemic embolism for patients with
atrial fibrillation by two-thirds, but its benefits for patients with previous intracranial …