User profiles for "author:Peter J Mitchell"

Peter J Mitchell

Director of Neurointervention, The Royal Melbourne Hospital
Verified email at mh.org.au
Cited by 38443

Extending thrombolysis to 4· 5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data

BCV Campbell, H Ma, PA Ringleb, MW Parsons… - The Lancet, 2019 - thelancet.com
Background Stroke thrombolysis with alteplase is currently recommended 0–4· 5 h after
stroke onset. We aimed to determine whether perfusion imaging can identify patients with …

Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a …

BCV Campbell, CBLM Majoie, GW Albers… - The Lancet …, 2019 - thelancet.com
Background CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection
for endovascular thrombectomy. We aimed to establish whether imaging assessments of …

Endovascular stent thrombectomy: the new standard of care for large vessel ischaemic stroke

BCV Campbell, GA Donnan, KR Lees… - The Lancet …, 2015 - thelancet.com
Background Results of initial randomised trials of endovascular treatment for ischaemic
stroke, published in 2013, were neutral but limited by the selection criteria used, early …

[HTML][HTML] Endovascular therapy for ischemic stroke with perfusion-imaging selection

BCV Campbell, PJ Mitchell, TJ Kleinig… - … England Journal of …, 2015 - Mass Medical Soc
Background Trials of endovascular therapy for ischemic stroke have produced variable
results. We conducted this study to test whether more advanced imaging selection, recently …

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials

M Goyal, BK Menon, WH Van Zwam, DWJ Dippel… - The Lancet, 2016 - thelancet.com
Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy
over standard medical care in patients with acute ischaemic stroke caused by occlusion of …

Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis

JL Saver, M Goyal, AAD Van der Lugt, BK Menon… - Jama, 2016 - jamanetwork.com
Importance Endovascular thrombectomy with second-generation devices is beneficial for
patients with ischemic stroke due to intracranial large-vessel occlusions. Delineation of the …

[HTML][HTML] Tenecteplase versus alteplase before thrombectomy for ischemic stroke

BCV Campbell, PJ Mitchell, L Churilov… - … England Journal of …, 2018 - Mass Medical Soc
Background Intravenous infusion of alteplase is used for thrombolysis before endovascular
thrombectomy for ischemic stroke. Tenecteplase, which is more fibrin-specific and has …

[HTML][HTML] Thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke

H Ma, BCV Campbell, MW Parsons… - … England Journal of …, 2019 - Mass Medical Soc
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is
generally limited to within 4.5 hours after the onset of symptoms. Some trials have suggested …

Endovascular thrombectomy versus standard bridging thrombolytic with endovascular thrombectomy within 4· 5 H of stroke onset: an open-label, blinded-endpoint …

PJ Mitchell, B Yan, L Churilov, RJ Dowling, SJ Bush… - The Lancet, 2022 - thelancet.com
Background The benefit of combined treatment with intravenous thrombolysis before
endovascular thrombectomy in patients with acute ischaemic stroke caused by large vessel …

Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data

L San Román, BK Menon, J Blasco… - The Lancet …, 2018 - thelancet.com
Background Evidence regarding whether imaging can be used effectively to select patients
for endovascular thrombectomy (EVT) is scarce. We aimed to investigate the association …