[HTML][HTML] Association of HTRA1 mutations and familial ischemic cerebral small-vessel disease

K Hara, A Shiga, T Fukutake, H Nozaki… - … England Journal of …, 2009 - Mass Medical Soc
Background The genetic cause of cerebral autosomal recessive arteriopathy with subcortical
infarcts and leukoencephalopathy (CARASIL), which is characterized by ischemic …

A new amyloid β variant favoring oligomerization in Alzheimer's‐type dementia

T Tomiyama, T Nagata, H Shimada… - Annals of …, 2008 - Wiley Online Library
Objective Soluble oligomers of amyloid β (Aβ), rather than amyloid fibrils, have been
proposed to initiate synaptic and cognitive dysfunction in Alzheimer's disease (AD) …

Molecular cloning of cDNA coding for brain-specific 14-3-3 protein, a protein kinase-dependent activator of tyrosine and tryptophan hydroxylases.

T Ichimura, T Isobe, T Okuyama… - Proceedings of the …, 1988 - National Acad Sciences
The 14-3-3 protein is a family of acidic proteins present exclusively in the brain and is
believed to have a function in monoamine biosynthesis because of its ability to activate …

CSF biomarker variability in the Alzheimer's Association quality control program

N Mattsson, U Andreasson, S Persson… - Alzheimer's & …, 2013 - Wiley Online Library
Background The cerebrospinal fluid (CSF) biomarkers amyloid beta 1–42, total tau, and
phosphorylated tau are used increasingly for Alzheimer's disease (AD) research and patient …

The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain

T Honda, H Saitoh, M Masuko, T Katagiri-Abe… - Molecular brain …, 2000 - Elsevier
In an attempt to elucidate the molecular mechanisms underlying neuro-network formation in
the developing brain, we analyzed 130 proteolytic cleavage peptides of membrane proteins …

[HTML][HTML] SORL1 Is Genetically Associated with Late-Onset Alzheimer's Disease in Japanese, Koreans and Caucasians

A Miyashita, A Koike, G Jun, LS Wang, S Takahashi… - PloS one, 2013 - journals.plos.org
To discover susceptibility genes of late-onset Alzheimer's disease (LOAD), we conducted a
3-stage genome-wide association study (GWAS) using three populations: Japanese from …

Transethnic genome‐wide scan identifies novel Alzheimer's disease loci

GR Jun, J Chung, J Mez, R Barber… - Alzheimer's & …, 2017 - Wiley Online Library
Abstract Introduction Genetic loci for Alzheimer's disease (AD) have been identified in whites
of European ancestry, but the genetic architecture of AD among other populations is less …

[HTML][HTML] Serum microRNA miR-501-3p as a potential biomarker related to the progression of Alzheimer's disease

N Hara, M Kikuchi, A Miyashita, H Hatsuta… - Acta neuropathologica …, 2017 - Springer
MicroRNAs (miRNAs) are attractive molecules to utilize as one of the blood-based
biomarkers for neurodegenerative disorders such as Alzheimer's disease (AD) because …

[HTML][HTML] AlzPathway: a comprehensive map of signaling pathways of Alzheimer's disease

S Mizuno, R Iijima, S Ogishima, M Kikuchi… - BMC systems …, 2012 - Springer
Background Alzheimer's disease (AD) is the most common cause of dementia among the
elderly. To clarify pathogenesis of AD, thousands of reports have been accumulating …

Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis

M Ito, M Kodama, M Masuko, M Yamaura… - Circulation …, 2000 - Am Heart Assoc
The expression of coxsackievirus and adenovirus receptor (CAR) was dominant in the
brains and hearts of mice until the newborn phase. There is no detailed information …