[HTML][HTML] Language dysfunction-associated EEG findings in patients with CAR-T related neurotoxicity
Chimeric antigen receptor-modified T cells (CAR-T) have emerged as a promising
immunotherapeutic approach in relapsed/refractory haematolgical malignancies. Broader …
immunotherapeutic approach in relapsed/refractory haematolgical malignancies. Broader …
Allogeneic anti-BCMA CAR T cells are superior to multiple myeloma-derived CAR T cells in preclinical studies and may be combined with gamma secretase inhibitors
AM Metelo, A Jozwik, LA Luong, D Dominey-Foy… - Cancer Research …, 2022 - AACR
Multiple myeloma remains an incurable plasma cell malignancy despite the rapidly evolving
treatment landscape. Chimeric antigen receptor T cells targeted against BCMA have …
treatment landscape. Chimeric antigen receptor T cells targeted against BCMA have …
Thermostable small-molecule inhibitor of angiogenesis and vascular permeability that suppresses a pERK-FosB/ΔFosB–VCAM-1 axis
Y Li, AMN Alhendi, MC Yeh, M Elahy, FS Santiago… - Science …, 2020 - science.org
Vascular permeability and angiogenesis underpin neovascular age-related macular
degeneration and diabetic retinopathy. While anti-VEGF therapies are widely used clinically …
degeneration and diabetic retinopathy. While anti-VEGF therapies are widely used clinically …
Similar outcomes of alemtuzumab-based hematopoietic cell transplantation for SAA patients older or younger than 50 years
VS Sheth, V Potter, SA Gandhi… - Blood …, 2019 - ashpublications.org
Survival after allogeneic hematopoietic cell transplantation (HSCT) for severe aplastic
anemia (SAA) among older patients remains poor and associated with increased risk for …
anemia (SAA) among older patients remains poor and associated with increased risk for …
The 10-metre gait speed as a functional biomarker in amyotrophic lateral sclerosis
S Inam, S Vucic, NE Brodaty, MC Zoing… - Amyotrophic Lateral …, 2010 - Taylor & Francis
There remains a critical need to develop biomarkers of disease progression in amyotrophic
lateral sclerosis (ALS). Mobility is a key determinant of disease status and quality of life. The …
lateral sclerosis (ALS). Mobility is a key determinant of disease status and quality of life. The …
Radiation exposure during cardiac catheterisation is similar for both femoral and radial approaches
Objectives Radial approach invasive coronary angiography has been shown to be superior
to the femoral approach in terms of reducing vascular access complications and improving …
to the femoral approach in terms of reducing vascular access complications and improving …
[HTML][HTML] Human herpesvirus 6 encephalitis following axicabtagene ciloleucel treatment for refractory diffuse large B cell lymphoma
M Shah, A Kuhnl, G Shields, M Sudhanva… - …, 2021 - journals.lww.com
The recent use of chimeric antigen receptor T cells (CAR-T) products has led to a shift in the
management of chemotherapy refractory high grade B cell lymphomas as well as B acute …
management of chemotherapy refractory high grade B cell lymphomas as well as B acute …
GB261, an Fc-Function enabled and CD3 affinity De-tuned CD20/CD3 bispecific antibody, demonstrated a highly advantageous Safety/Efficacy balance in an ongoing …
Y Song, Z Li, L Li, Z Qian, K Zhou, L Fan, P Tan, P Giri… - Blood, 2023 - Elsevier
Introduction: GB261 is a novel and highly differentiated CD20/CD3 bispecific T cell engager
antibody computationally designed to maintain Fc effector function, ie, antibody-dependent …
antibody computationally designed to maintain Fc effector function, ie, antibody-dependent …
Paving the way to precision medicine in multiple myeloma
S Inam, JA Ross, C Touzeau, P Moreau… - Expert Review of …, 2021 - Taylor & Francis
Our understanding of the pathobiology of multiple myeloma (MM) and its treatment have
progressed substantially over past decades. While risk stratification including …
progressed substantially over past decades. While risk stratification including …
[HTML][HTML] Third-party partially HLA matched fungus-specific T-cells (FSTs) used to treat invasive fungal infection (IFI) with scedosporium aurantiacum after allogeneic …
S Inam, G Sutrave, S Avdic, J Street, E Atkins… - Blood, 2021 - Elsevier
Introduction Invasive fungal infection (IFI) is a potentially devastating complication after
allogeneic stem cell transplantation (aHSCT). Breakthrough infections are an increasing …
allogeneic stem cell transplantation (aHSCT). Breakthrough infections are an increasing …