Neurofilament levels in CSF and serum in an adult SMA cohort treated with Nusinersen

KA Rich, A Fox, M Yalvac, S Heintzman… - Journal of …, 2022 - content.iospress.com
Objective: To retrospectively evaluate the utility of serum and cerebrospinal fluid (CSF)
levels of neurofilament light chain (NfL) and phosphorylated neurofilament heavy chain …

[HTML][HTML] Safety, tolerability, and effect of nusinersen treatment in ambulatory adults with 5q-SMA

B Elsheikh, S Severyn, S Zhao, D Kline… - Frontiers in …, 2021 - frontiersin.org
Objective: To determine the safety and tolerability of nusinersen treatment in ambulatory
adults with spinal muscular atrophy (SMA) and investigate the treatment effect on muscle …

[HTML][HTML] Persistent neuromuscular junction transmission defects in adults with spinal muscular atrophy treated with nusinersen

WD Arnold, S Severyn, S Zhao, D Kline… - BMJ neurology …, 2021 - ncbi.nlm.nih.gov
Objective Spinal muscular atrophy (SMA) is a motor neuron disease caused by low levels of
survival motor neuron (SMN) protein. Prior work in models and patients has demonstrated …

[HTML][HTML] Long-term efficacy of a novel spinal cord stimulation clinical workflow using kilohertz stimulation: twelve-month results from the vectors study

JA Hatheway, V Mangal, MA Fishman, P Kim… - … : Technology at the …, 2021 - Elsevier
Abstract Background and Objectives Multiple variables play a role in spinal cord stimulation
(SCS) treatment outcomes, including patient anatomy, pain pattern, lead location …

[HTML][HTML] Safety, tolerability, and effect of nusinersen in non-ambulatory adults with spinal muscular atrophy

B Elsheikh, S Severyn, S Zhao, D Kline… - Frontiers in …, 2021 - frontiersin.org
Objective: Investigation of the safety, tolerability, and treatment effect of nusinersen treatment
in non-ambulatory adults with spinal muscular atrophy (SMA). Methods: Non-ambulatory …

The qualifications of pain physicians in Ohio

RM Buenaventura, TD McSweeney… - Anesthesia & …, 2005 - journals.lww.com
IMPLICATIONS: We analyzed the members of several pain medicine boards by using
published directories and Internet databases. The American Board of Medical Specialties …

Impact of Nusinersen treatment on quality of life in adult patients with Spinal Muscular Atrophy (P3-8.010)

FG Castanon, A Deardorff, S Zhao, S Severyn, K Kelly… - 2023 - AAN Enterprises
Objective: Investigate quality of life (QoL) in adults with genetically proven Spinal Muscular
Atrophy (SMA) at baseline and after 14 months of Nusinersen therapy. Background …

Quality of Life in Adults with Spinal Muscular Atrophy (2716)

CA Bermudez, S Frank, SJ Kolb, WD Arnold, S Severyn… - 2020 - AAN Enterprises
Objective: 1. To characterize factors influencing health-related quality of life (Qol). 2. To track
changes in Qol overtime after treatment with disease-modifying therapy in a cohort of adult …

Minimally Invasive Interventions for Headache

SA Severyn, AM Afifi, EL MacKenzie - Surgical Treatment of Chronic …, 2020 - Springer
The array of minimally invasive interventions for chronic head and neck pain has grown
rapidly with the advent of technologies that allow for targeting of various components of the …

Investigating NMJ transmission failure in Adults with Spinal Muscular Atrophy (2362)

B Elsheikh, S Kolb, S Severyn, M Linsenmayer, K Kelly… - 2020 - AAN Enterprises
Objective: The objectives of the current study were to: 1. Examine adult individuals (> 18
years of age) with spinal muscular atrophy (SMA) for evidence of neuromuscular junction …